@article{42023,
author = "Winfried Ilg and Sarah Milne and Tanja Schmitz‑H{\"u}bsch and Lisa Alcock and  Lukas Beichert and Enrico Bertini and Norlinah Mohamed Ibrahim and Helen Dawes and Christopher M. Gomez and  Hasmet Hanagasi and Kirsi M. Kinnunen and Martina Minnerop and Andrea H. N{\'e}meth and Jane Newman and  Yi Shiau Ng and Clara Rentz and Bedia Samanci and Vrutangkumar V. Shah and Susanna Summa and  Gessica Vasco and James McNames and Fay B. Horak",
abstract = "With disease-modifying drugs on the horizon for degenerative ataxias, ecologically valid, fnely granulated, digital health 
measures are highly warranted to augment clinical and patient-reported outcome measures. Gait and balance disturbances 
most often present as the frst signs of degenerative cerebellar ataxia and are the most reported disabling features in disease 
progression. Thus, digital gait and balance measures constitute promising and relevant performance outcomes for clinical 
trials.
This narrative review with embedded consensus will describe evidence for the sensitivity of digital gait and balance measures for evaluating ataxia severity and progression, propose a consensus protocol for establishing gait and balance metrics 
in natural history studies and clinical trials, and discuss relevant issues for their use as performance outcomes.",
doi = "https://doi.org/10.1007/s12311-023-01625-2",
journal = "The Cerebellum",
month = " 20 October 2023",
title = "{Q}uantitative {G}ait and {B}alance {O}utcomes for {A}taxia {T}rials: {C}onsensus {R}ecommendations by the {A}taxia {G}lobal {I}nitiative {W}orking {G}roup on {D}igital-{M}otor {B}iomarkers",
url = "https://link.springer.com/article/10.1007/s12311-023-01625-2",
year = "2023",
files = "AGI_gaitbalance_consensus_final.pdf",
}